USA
Analytical Standards
Controlled Research Environment
Research Product
Kisspeptin-10
1. Product Overview
Kisspeptin-10 is a synthetic decapeptide derived from the active region of the kisspeptin protein family. It has attracted scientific interest in research involving reproductive endocrinology, neuroendocrine signaling, hypothalamic-pituitary-gonadal (HPG) axis regulation, and peptide receptor interactions. Ongoing studies continue to explore its role in hormone signaling pathways and reproductive biology. Kisspeptin-10 is supplied as a lyophilized research peptide and undergoes analytical testing to verify identity, purity, and consistency.
Manufactured in a controlled research environment, this product is intended exclusively for laboratory and scientific research applications.
2. Specifications
| Product Name | Kisspeptin-10 | Testing Method | HPLC |
|---|---|---|---|
| Synonym | Metastin (45-54) / Kisspeptin-10 | Storage Condition | 2-8C |
| Format | Lyophilized Powder | Shelf Life | 24 Months |
| Content | 5 mg per vial | Manufacturing Standard | GMP Standard Research Environment |
| Purity | >=99% HPLC | Country of Origin | USA |
| Appearance | White to Off White Lyophilized Powder | Intended Use | Research Use Only |
3. Research Summary
Kisspeptin-10 is a synthetic decapeptide derived from the biologically active region of the kisspeptin protein family. It has attracted significant scientific interest in studies involving reproductive endocrinology, neuroendocrine signaling, hypothalamic-pituitary-gonadal (HPG) axis regulation, gonadotropin-releasing hormone (GnRH) pathways, and peptide receptor interactions.
Research has explored the interaction of Kisspeptin-10 with the GPR54 (KISS1R) receptor and its role in reproductive hormone signaling, neuroendocrine communication, and physiological regulation mechanisms. Ongoing laboratory investigations continue to evaluate its activity within endocrine and reproductive biology research models.
4. Scientific References
- Kotani M, Detheux M, Vandenbogaerde A, et al. The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of GPR54. Journal of Biological Chemistry. 2001;276(37):34631-34636.
- Messager S, Chatzidaki EE, Ma D, et al. Kisspeptin directly stimulates gonadotropin-releasing hormone release via GPR54. Proceedings of the National Academy of Sciences. 2005;102(5):1761-1766.
- Seminara SB, Messager S, Chatzidaki EE, et al. The GPR54 gene as a regulator of puberty and reproductive function. New England Journal of Medicine. 2003;349(17):1614-1627.
- Oakley AE, Clifton DK, Steiner RA. Kisspeptin signaling in the brain. Endocrine Reviews. 2009;30(6):713-743.
- Pinilla L, Aguilar E, Dieguez C, Millar RP, Tena-Sempere M. Kisspeptins and reproduction: Physiological roles and regulatory mechanisms. Physiological Reviews. 2012;92(3):1235-1316.
Disclaimer: This product is intended strictly for research use only. It is not intended for human consumption, clinical application, diagnostic procedures, therapeutic use, veterinary use, or household use. The information provided is for scientific and educational reference purposes only and should not be interpreted as medical advice, treatment guidance, or usage instructions. This product should be handled only by qualified professionals trained in laboratory practices. Purchasers and end users are solely responsible for ensuring compliance with all applicable laws, regulations, and institutional requirements governing the purchase, storage, handling, and use of research materials.
