USA
Analytical Standards
Controlled Research Environment
Research Product
TB-500
1. Product Overview
TB-500 is a synthetic research peptide derived from the active region of Thymosin Beta-4. It has attracted significant scientific interest in studies involving cellular migration, tissue remodeling, angiogenesis, extracellular matrix regulation, and regenerative biological pathways. Ongoing research continues to explore its interaction with cellular signaling mechanisms and tissue response processes. TB-500 is supplied as a lyophilized research peptide and undergoes analytical testing to verify identity, purity, and consistency.
Manufactured in a controlled research environment, this product is intended exclusively for laboratory and scientific research applications.
2. Specifications
| Product Name | TB-500 | Testing Method | HPLC |
|---|---|---|---|
| Synonym | Thymosin Beta-4 Fragment | Storage Condition | 2-8C |
| Format | Lyophilized Powder | Shelf Life | 24 Months |
| Content | 5 mg per vial | Manufacturing Standard | GMP Standard Research Environment |
| Purity | >=99% HPLC | Country of Origin | USA |
| Appearance | White to Off White Lyophilized Powder | Intended Use | Research Use Only |
3. Research Summary
TB-500 is a synthetic research peptide derived from the active region of Thymosin Beta-4, a naturally occurring protein involved in cellular migration and tissue organization. It has attracted significant scientific interest in studies involving cellular signaling, angiogenesis, extracellular matrix regulation, tissue remodeling, and regenerative biological pathways.
Preclinical research has explored the role of Thymosin Beta-4-related peptides in cellular movement, cytoskeletal organization, wound healing models, and tissue response mechanisms. Ongoing investigations continue to evaluate the biological functions of TB-500 in laboratory settings involving cellular adaptation and regenerative research.
4. Scientific References
- Goldstein AL, Hannappel E, Kleinman HK. Thymosin β4: Actin-sequestering protein moonlights to repair injured tissues. Trends in Molecular Medicine. 2005;11(9):421-429.
- Malinda KM, Goldstein AL, Kleinman HK. Thymosin beta 4 stimulates directional migration of human umbilical vein endothelial cells. FASEB Journal. 1997;11(7):474-481.
- Smart N, Risebro CA, Melville AA, et al. Thymosin β4 induces adult epicardial progenitor mobilization and neovascularization. Nature. 2007;445(7124):177-182.
- Sosne G, Qiu P, Goldstein AL, Wheater M. Biological activities of thymosin β4 defined by active sites in short peptide sequences. FASEB Journal. 2010;24(7):2144-2151.
- Huff T, Müller CSG, Otto AM, Netzker R, Hannappel E. β-Thymosins, small acidic peptides with multiple functions. International Journal of Biochemistry & Cell Biology. 2001;33(3):205-220.
Disclaimer: This product is intended strictly for research use only. It is not intended for human consumption, clinical application, diagnostic procedures, therapeutic use, veterinary use, or household use. The information provided is for scientific and educational reference purposes only and should not be interpreted as medical advice, treatment guidance, or usage instructions. This product should be handled only by qualified professionals trained in laboratory practices. Purchasers and end users are solely responsible for ensuring compliance with all applicable laws, regulations, and institutional requirements governing the purchase, storage, handling, and use of research materials.
