USA
Analytical Standards
Controlled Research Environment
Research Product
5-Amino-1MQ
1. Product Overview
5-Amino-1MQ is a synthetic research compound that has attracted scientific interest in studies involving cellular metabolism, energy regulation, nicotinamide N-methyltransferase (NNMT) pathways, and metabolic signaling mechanisms. Ongoing preclinical research continues to explore its interaction with biological processes associated with cellular energy balance and metabolic function. 5-Amino-1MQ is supplied as a lyophilized research formulation and undergoes analytical testing to verify identity, purity, and consistency.
Manufactured in a controlled research environment, this product is intended exclusively for laboratory and scientific research applications.
2. Specifications
| Product Name | 5-Amino-1MQ | Testing Method | HPLC |
|---|---|---|---|
| Synonym | 5-Amino-1MQ peptide profile | Storage Condition | 2-8C |
| Format | Lyophilized Powder | Shelf Life | 24 Months |
| Content | 25 mg per vial | Manufacturing Standard | GMP Standard Research Environment |
| Purity | >=99% HPLC | Country of Origin | USA |
| Appearance | Amber Orange Lyophilized Powder | Intended Use | Research Use Only |
3. Research Summary
5-Amino-1MQ is a synthetic research compound that has attracted scientific interest due to its interaction with nicotinamide N-methyltransferase (NNMT), an enzyme involved in cellular metabolism and energy regulation. Preclinical research has explored the compound's influence on metabolic pathways associated with energy expenditure, adipocyte biology, cellular fuel utilization, and metabolic homeostasis. Ongoing studies continue to investigate its role in NNMT-related signaling mechanisms and broader metabolic research applications.
Research involving 5-Amino-1MQ remains primarily preclinical and laboratory-based. The compound is utilized in scientific investigations focused on metabolism, cellular energy balance, and biochemical pathway analysis.
4. Scientific References
- Kraus D, Yang Q, Kong D, et al. Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity. Nature. 2014;508(7495):258-262.
- Neelakantan H, Vance V, Wetzel MD, et al. Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice. Biochemical Pharmacology. 2018;147:141-152.
- Kannt A, Rajagopal S, Kadnur SV, et al. A small molecule inhibitor of Nicotinamide N-Methyltransferase for the treatment of metabolic disorders. Scientific Reports. 2018;8:3660.
- Ulanovskaya OA, Zuhl AM, Cravatt BF. NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sink. Nature Chemical Biology. 2013;9(5):300-306.
- Roberti A, Fernández AF, Fraga MF. Nicotinamide N-methyltransferase: At the crossroads between cellular metabolism and epigenetic regulation. Molecular Metabolism. 2021;45:101165.
Disclaimer: This product is intended strictly for research use only. It is not intended for human consumption, clinical application, diagnostic procedures, therapeutic use, veterinary use, or household use. The information provided is for scientific and educational reference purposes only and should not be interpreted as medical advice, treatment guidance, or usage instructions. This product should be handled only by qualified professionals trained in laboratory practices. Purchasers and end users are solely responsible for ensuring compliance with all applicable laws, regulations, and institutional requirements governing the purchase, storage, handling, and use of research materials.
