USA
Analytical Standards
Controlled Research Environment
Research Product
Follistatin 344
1. Product Overview
Follistatin 344 is a recombinant research peptide that has attracted scientific interest for its interaction with members of the transforming growth factor-beta (TGF-β) superfamily, particularly activin and myostatin-related signaling pathways. Ongoing research has explored its role in cellular growth regulation, tissue development, protein expression, and skeletal muscle biology. Follistatin 344 is supplied as a lyophilized research peptide and undergoes analytical testing to verify identity, purity, and consistency.
Manufactured in a controlled research environment, this product is intended exclusively for laboratory and scientific research applications.
2. Specifications
| Product Name | Follistatin 344 | Testing Method | HPLC |
|---|---|---|---|
| Synonym | Follistatin 344 peptide profile | Storage Condition | 2-8C |
| Format | Lyophilized Powder | Shelf Life | 24 Months |
| Content | 1 mg per vial | Manufacturing Standard | GMP Standard Research Environment |
| Purity | >=99% HPLC | Country of Origin | USA |
| Appearance | White to Off White Lyophilized Powder | Intended Use | Research Use Only |
3. Research Summary
Follistatin 344 (FST-344) is a recombinant research peptide that has attracted significant scientific interest for its interaction with members of the transforming growth factor-beta (TGF-β) superfamily, particularly activin and myostatin-related signaling pathways. Research has explored its role in cellular growth regulation, tissue development, protein expression, skeletal muscle biology, and cellular differentiation mechanisms.
Preclinical investigations have examined the interaction of Follistatin 344 with biological pathways involved in growth factor signaling, tissue homeostasis, and cellular adaptation. Ongoing laboratory studies continue to evaluate its role in myostatin-related research, regenerative biology, and growth factor-mediated cellular processes.
4. Scientific References
- Lee SJ, McPherron AC. Regulation of myostatin activity and muscle growth. Proceedings of the National Academy of Sciences. 2001;98(16):9306-9311.
- Amthor H, Nicholas G, McKinnell I, et al. Follistatin complexes Myostatin and antagonizes Myostatin-mediated inhibition of myogenesis. Developmental Biology. 2004;270(1):19-30.
- Nakatani M, Takehara Y, Sugino H, Matsumoto M, Hashimoto O, Hasegawa Y. Transgenic expression of Follistatin induces muscle hypertrophy through modulation of myostatin signaling. American Journal of Physiology Endocrinology and Metabolism. 2008;294(4):E699-E707.
- Gilson H, Schakman O, Kalista S, et al. Follistatin induces muscle hypertrophy through satellite cell proliferation and inhibition of myostatin signaling. American Journal of Physiology Cell Physiology. 2009;297(5):C1124-C1134.
- Lee SJ. Extracellular regulation of myostatin: A molecular rheostat for muscle mass. Immunology, Endocrine & Metabolic Agents in Medicinal Chemistry. 2010;10(3):183-194.
Disclaimer: This product is intended strictly for research use only. It is not intended for human consumption, clinical application, diagnostic procedures, therapeutic use, veterinary use, or household use. The information provided is for scientific and educational reference purposes only and should not be interpreted as medical advice, treatment guidance, or usage instructions. This product should be handled only by qualified professionals trained in laboratory practices. Purchasers and end users are solely responsible for ensuring compliance with all applicable laws, regulations, and institutional requirements governing the purchase, storage, handling, and use of research materials.
